Sorfequiline, previously known as TBAJ-876, was evaluated in combination with pretomanid and linezolid in a randomized, controlled trial in people with drug-sensitive TB COPENHAGEN (November 19, 2025)—New clinical trial results presented by TB Alliance at the Union World Conference on Lung Health show that the novel antibiotic candidate sorfequiline (TBAJ-876), a next-generation diarylquinoline, has the…
No, bitter leaf cannot cure malaria – ignore dangerous claims and seek verified medical treatment IN SHORT: Claims that bitter leaf contains quinine and can cure malaria are false. Experts warn that this is dangerous information and that patients with malaria must seek effective treatment with quality medication. According to posts doing the rounds on…
The COVID-19 mRNA-based vaccines that saved 2.5 million lives globally during the pandemic could help spark the immune system to fight cancer. This is the surprising takeaway of a new study that we and our colleagues published in the journal Nature. While developing mRNA vaccines for patients with brain tumors in 2016, our team, led…
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The World Health Organization (WHO) has published its global cholera statistics for 2024, showing an increase in both the number of people who fell sick and died from the disease. Reported cholera cases rose by 5% and deaths by 50% in 2024 compared to 2023, with more than 6000 people dying from a disease that…
New infant-friendly formulation closes a critical treatment gap for the youngest children, with support from African-led trials and global partners. Addis Ababa, 16 August 2025 – The Africa Centres for Disease Control and Prevention (Africa CDC) welcomes the approval of the first malaria treatment specifically formulated for newborns and infants weighing less than five kilogrammes…
The Africa Centres for Disease Control and Prevention (Africa CDC) applauded Nigeria for its role in the trials in a statement on Sunday. Nigeria has been named among eight African countries that contributed to a clinical trial leading to the approval of the first malaria treatment for newborns and infants weighing less than five kilogrammes….
The first malaria treatment for babies and very young children of 2 months up to 5 years was approved for use by Swiss agency for therapeutic products, Swissmedic, in early July 2025. Until now, babies and very young children have been treated with medicines formulated for older children. The Conversation Africa asked Fortunate Mokoena, about…
Monrovia — The World Health Organization (WHO) released new guidelines for the treatment and management of arboviral diseases, which are illnesses caused by viruses transmitted to humans through Aedes mosquitoes, . Arboviruses can cause a range of similar symptoms, from mild flu-like symptoms to severe, potentially life-threatening conditions like encephalitis or hemorrhagic fever. The new…
Mayeni Jones BBC News, Johannesburg Reuters Gugu used to collect her antiretrovirals from a USAID-funded clinic in central Johannesburg. But when President Trump’s cuts to aid funding were announced earlier this year, she and thousands of other HIV-positive patients across South Africa suddenly faced an uncertain future. Gugu was lucky, the clinic where she got…
