Sorfequiline, previously known as TBAJ-876, was evaluated in combination with pretomanid and linezolid in a randomized, controlled trial in people with drug-sensitive TB COPENHAGEN (November 19, 2025)—New clinical trial results presented by TB Alliance at the Union World Conference on Lung Health show that the novel antibiotic candidate sorfequiline (TBAJ-876), a next-generation diarylquinoline, has the…
Brazzaville/Oslo — New funding to the AdVAncIng Clinical TRials Excellence in Africa (AVAREF) could help accelerate the development of life-saving vaccines to contain infectious disease outbreaks on the continent. The Coalition for Epidemic Preparedness Innovations (CEPI) is providing $1 million to AVAREF as part of a new two-year project to enhance the efficiency with which…
Some of the world’s largest funders of medical research have today committed, through the signature of a joint statement, to implement WHO standards to strengthen clinical trial systems and ensure that research better serves patients and communities. The statement sets out measures to integrate clinical trials into sustainable national infrastructure, improve trial design, ensure that…
